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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YWHAG
All Species:
32.12
Human Site:
Y85
Identified Species:
54.36
UniProt:
P61981
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61981
NP_036611.2
247
28303
Y85
K
I
E
M
V
R
A
Y
R
E
K
I
E
K
E
Chimpanzee
Pan troglodytes
XP_519163
321
36086
Y159
K
I
E
M
V
R
A
Y
R
E
K
I
E
K
E
Rhesus Macaque
Macaca mulatta
XP_001111955
233
26714
R73
L
E
K
V
K
A
Y
R
E
K
I
E
K
E
L
Dog
Lupus familis
XP_546936
343
38553
Y181
K
I
E
M
V
R
A
Y
R
E
K
I
E
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV8
246
28068
Q79
E
R
N
E
K
K
Q
Q
M
G
K
E
Y
R
E
Rat
Rattus norvegicus
P61983
247
28284
Y85
K
I
E
M
V
R
A
Y
R
E
K
I
E
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505266
247
28347
Y85
K
L
E
K
V
K
A
Y
R
E
K
I
E
K
E
Chicken
Gallus gallus
Q5F3W6
247
28212
Y85
K
I
E
M
V
R
A
Y
R
E
K
I
E
K
E
Frog
Xenopus laevis
Q6PCG0
247
28255
Y85
K
I
E
M
V
R
A
Y
R
E
K
I
E
K
E
Zebra Danio
Brachydanio rerio
Q6PC29
247
28216
Y85
K
I
E
M
V
R
A
Y
R
E
K
I
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
R77
Q
K
T
E
A
S
A
R
K
Q
Q
L
A
R
E
Honey Bee
Apis mellifera
XP_391841
247
28058
R76
Q
K
T
E
G
S
E
R
K
Q
Q
M
A
K
E
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
G73
S
I
E
Q
K
T
E
G
S
E
K
K
Q
Q
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34730
273
31043
S86
H
Q
V
E
L
I
R
S
Y
R
S
K
I
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.9
78.1
67.3
N.A.
76.5
100
N.A.
80.1
99.5
98.7
95.9
N.A.
73.3
77.3
74.5
N.A.
Protein Similarity:
100
76.9
84.6
69.3
N.A.
86.6
100
N.A.
87
99.5
99.1
98.3
N.A.
83.8
85.4
85.4
N.A.
P-Site Identity:
100
100
0
100
N.A.
13.3
100
N.A.
80
100
100
100
N.A.
13.3
13.3
26.6
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
33.3
100
N.A.
93.3
100
100
100
N.A.
53.3
46.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
57.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
65
0
0
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
65
29
0
0
15
0
8
65
0
15
58
15
79
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
0
8
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
58
0
0
0
8
0
0
0
0
8
58
8
0
0
% I
% Lys:
58
15
8
8
22
15
0
0
15
8
72
15
8
65
0
% K
% Leu:
8
8
0
0
8
0
0
0
0
0
0
8
0
0
8
% L
% Met:
0
0
0
50
0
0
0
0
8
0
0
8
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
8
0
8
0
0
8
8
0
15
15
0
8
8
0
% Q
% Arg:
0
8
0
0
0
50
8
22
58
8
0
0
0
15
0
% R
% Ser:
8
0
0
0
0
15
0
8
8
0
8
0
0
0
0
% S
% Thr:
0
0
15
0
0
8
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
8
8
58
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
58
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _